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Rabbit anti-Phospho XRCC1 (S518/T519/T523) IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
XRCC1 Phospho (S518/T519/T523)
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Surrounding serine 518 and threonine 519/523
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $490.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Antigen Species
Human
Concentration
50 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to Phospho XRCC1 (S518/T519/T523) immobilized on solid support.

The epitope recognized by IHC-00115 maps to a region surrounding residues Ser 518, Thr 519 and Thr 523 of human X-ray Repair Complementing protein 1 using the numbering given in SwissProt enty P18887 (GeneID 7515).
Antibody was affinity purified using an epitope specific to Phospho XRCC1 (S518/T519/T523) immobilized on solid support.

The epitope recognized by IHC-00115-T maps to a region surrounding residues Ser 518, Thr 519 and Thr 523 of human X-ray Repair Complementing protein 1 using the numbering given in SwissProt enty P18887 (GeneID 7515).
Country of Origin
USA

Additional Product Information

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and DNA ligase III in a multiprotein complex to execute the function of DNA repair.

7515
XRCC1
X-ray repair cross complementing 1
P18887
DNA repair protein XRCC1

Alternate Names

DNA repair protein XRCC1; RCC; SCAR26; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.