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Rabbit anti-PML Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
PML
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 575 and 625
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
40 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to PML immobilized on solid support.

The epitope recognized by A301-168A-T maps to a region between residue 575 and 625 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).

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Gene & Protein Information

PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.

5371

PML

promyelocytic leukemia

P29590

Protein PML

Alternate Names

MYL, PML/RARA fusion, PP8675, probable transcription factor PML, promyelocytic leukemia protein, promyelocytic leukemia, inducer of, protein PML, RING finger protein 71, RNF71, TRIM19, tripartite motif protein TRIM19, tripartite motif-containing protein 19

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.

Citations (4)