Bethyl Laboratories
Rabbit anti-PNUTS IHC Antibody Affinity Purified
Primary
Catalog #IHC-00050
TargetPNUTS
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
PNUTS (PP1 nuclear targeting subunit) is a regulatory subunit of the PP1 protein phosphatase, a serine/threonine phosphatase involved in mitotic exit and chromosome decondensation. PNUTS has been shown to play a role in targeting PP1 to the nucleus and mediating PP1 association to specific RNAs.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 375 and 425
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
500 µg/ml
Target Identity
TargetPNUTS
Antigen Species
Human
Gene ID5514
Gene Symbol
PPP1R10
Gene Name
protein phosphatase 1 regulatory subunit 10
Uniprot IDQ96QC0
Protein Name
Serine/threonine-protein phosphatase 1 regulatory subunit 10
Alternate Names
CAT53 • FB19 • HLA-C associated transcript 53 • MHC class I region proline-rich protein CAT53 • p99 • phosphatase 1 nuclear targeting subunit • PNUTS • PP1-binding protein of 114 kDa • PP1R10 • Protein FB19 • protein phosphatase 1, regulatory (inhibitor) subunit 10 • R111 • serine/threonine-protein phosphatase 1 regulatory subunit 10 • testis tissue sperm-binding protein Li 67n
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to PNUTS immobilized on solid support.
The epitope recognized by IHC-00050 maps to a region between residue 350 and 400 of human Phosphatase Nuclear Targeting Subunit (a.k.a. Protein Phosphatase 1, regulatory subunit 10) using the numbering given in TrEMBL entry Q96QC0 (GeneID 5514).
Applications
Epitope exposure is recommended.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00050Open
Product DatasheetPDF · IHC-00050 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00050 · Lot 1 (current lot)Open
Citations / Publications
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