Rabbit anti-PPAR-gamma Antibody Affinity Purified
Catalog #
PPAR-gamma
Human
,Mouse
IP
Rabbit
Polyclonal
Whole IgG
Between 100 and 150
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Dog,
Pig,
Monkey
Pig,
Monkey
Monkey
Human
2 - 8 °C
1 year from date of receipt
USA
PPAR-gamma is a nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. PPAR-gamma is a key regulator of adipocyte differentiation and glucose homeostasis and acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P37231].
Peroxisome proliferator-activated receptor gamma
Alternate Names
CIMT1; GLM1; NR1C3; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; PPARG1; PPARG2; PPARgamma; PPAR-gamma
Applications