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Primary Antibodies  

Rabbit anti-PPIP5K2 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PPIP5K2

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

PPIP5K2 is a bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. PPPIP5K2 phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, PPIP5K2 phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43314].

23262

PPIP5K2

diphosphoinositol pentakisphosphate kinase 2

O43314

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

Alternate Names

CFAP160; deafness, autosomal recessive 100; DFNB100; Diphosphoinositol pentakisphosphate kinase 2; HISPPD1; histidine acid phosphatase domain-containing protein 1; hsVIP2; inositol heptaphosphate kinase 2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; insP6 and PP-IP5 kinase 2; IP7K2; VIP1 homolog 2; VIP2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.