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Primary Antibodies  

Rabbit anti-PPP2R5C Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PPP2R5C

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 440 and 490

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Protein phosphatase 2, regulatory subunit B', gamma (PPP2R5C) is a regulatory subunit of the PP2A phosphatase. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13362].

5527

PPP2R5C

protein phosphatase 2 regulatory subunit B'gamma

Q13362

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

Alternate Names

B' alpha regulatory subunit; B56G; B56gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform B'-gamma; PP2A B subunit isoform PR61-gamma; PP2A B subunit isoform R5-gamma; PR61G; protein phosphatase 2 regulatory subunit B', gamma; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; protein phosphatase 2, regulatory subunit B', gamma isoform; renal carcinoma antigen NY-REN-29; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.