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Rabbit anti-PRKAR1A Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
PRKAR1A
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Orangutan
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to PRKAR1A immobilized on solid support.

The epitope recognized by A303-683A-T maps to a region between residue 1 and 50 of human Protein Kinase, cAMP-Dependent, Regulatory, Type I, Alpha using the numbering given in entry NP_002725.1 (GeneID 5573).

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Gene & Protein Information

cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) is the regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. PRKAR1A is also known as tissue-specific extinguisher 1 (TSE1); PRKAR1A was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in PRKAR1A cause Carney complex (CNC), a multiple neoplasia syndrome characterized by spotty skin pigmentation, cardiac and other myxomas, endocrine tumors, and psammomatous melanotic schwannomas [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10644].

5573

PRKAR1A

protein kinase cAMP-dependent type I regulatory su

P10644

cAMP-dependent protein kinase type I-alpha regulat

Alternate Names

ACRDYS1, ADOHR, cAMP-dependent protein kinase regulatory subunit RIalpha, cAMP-dependent protein kinase type I-alpha regulatory chain, cAMP-dependent protein kinase type I-alpha regulatory subunit, CAR, Carney complex type 1, CNC, CNC1, epididymis secretory sperm binding protein, PKR1, PPNAD1, PRKAR1, protein kinase A type 1a regulatory subunit, protein kinase, cAMP-dependent, regulatory subunit type I alpha, protein kinase, cAMP-dependent, regulatory, type I, alpha, tissue-specific extinguisher 1, TSE1

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.