NEW!

Rabbit anti-PRMT5 IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
PRMT5
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 587 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

$131.00 $492.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Presumed Reactivity
Guinea Pig, Horse, Dog, Pig, Rabbit, X. laevis, X. tropicalis, Bovine, Monkey
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to PRMT5 immobilized on solid support.

The epitope recognized by IHC-00146 maps to a region between residues 580 and the C-terminus (residue 637) of Protein Arginine Methyltransferase 5 using the numbering given in entry NP_006100.2 (GeneID 10419).
Antibody was affinity purified using an epitope specific to PRMT5 immobilized on solid support.

The epitope recognized by IHC-00146-T maps to a region between residues 580 and the C-terminus (residue 637) of Protein Arginine Methyltransferase 5 using the numbering given in entry NP_006100.2 (GeneID 10419).
Country of Origin
USA

Additional Product Information

Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.

10419
PRMT5
protein arginine methyltransferase 5
O14744
Protein arginine N-methyltransferase 5

Alternate Names

72 kDa ICln-binding protein; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; IBP72; jak-binding protein 1; JBP1; protein arginine N-methyltransferase 5; shk1 kinase-binding protein 1 homolog; SKB1; SKB1 homolog; SKB1Hs

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.