Rabbit anti-PUF60 Antibody
Catalog #
PUF60
Human
,Mouse
IHC
,WB
Rabbit
Polyclonal
Whole IgG
between 509 and 559
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Poly-U binding splicing factor 60KDa (PUF60) is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. PUF60 is implicated in the xeroderma pigmentosum disorder [taken from NCBI Entrez Gene (Gene ID: 22827)].
Alternate Names
60 kDa poly(U)-binding-splicing factor; FBP interacting repressor; FBP-interacting repressor; FIR; FUSE-binding protein-interacting repressor; poly(U) binding splicing factor 60KDa; poly(U)-binding-splicing factor PUF60; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; RoBPI; Siah binding protein 1; Siah-binding protein 1; SIAHBP1; Siah-BP1; VRJS
Applications