Rabbit anti-RAP80 Antibody Affinity Purified
Catalog #
RAP80
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 600 and 650
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
RAP80 was first identified as a nuclear protein that interacts with the retinoid-related testis-associated receptor (RTR) and is able to inhibit the interaction of RTR with the N-CoR co-repressor. RAP80 has also been shown to interact with estrogen receptor alpha (ER-alpha) and modulate its activity. The modulation of ER-alpha activity is dependent on the ubiquitin-interacting motif (UIM) of RAP80. The UIM of RAP80 has also been demonstrated to be important for the BRCA1-dependent DNA repair response.
Alternate Names
BRCA1-A complex subunit RAP80; RAP80; receptor-associated protein 80; retinoid X receptor-interacting protein 110; Ubiquitin interaction motif-containing protein 1; X2HRIP110
Applications