Rabbit anti-Raptor Antibody
Catalog #
Raptor
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Raptor (regulatory-associated protein of mTOR) is part of the rapamycin sensitive mTORC1 complex which includes mTOR, and mLst8/GbetaL. S6K and 4EBP1 are substrates of mTORC1 kinase activity. Raptor is required for mTOR’s ability to phosphorylate 4E-BP1 and physically interacts with 4EBP1 to act as a potential scaffold that bridges mTOR and 4EBP1 or S6K. The mTORC1 complex integrates cell signals to promote cell growth in response to growth factors.
Regulatory-associated protein of mTOR
Alternate Names
KOG1; Mip1; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; raptor; regulatory-associated protein of mTOR
Applications