Bethyl Laboratories
Rabbit anti-RbBP4 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00242
TargetRbBP4
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
RbBP4 is a member of the WD-repeat subfamily of proteins and is a component of multiple complexes involved in chromatin assembly, histone deacetylation, and transcriptional repression. RbBP4 has also been identified as a retinoblastoma (Rb) binding protein and plays a role in the repression of E2F-regulated genes in association with Rb and histone deacetylases.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetRbBP4
Antigen Species
Human
Gene ID5928
Gene Symbol
RBBP4
Gene Name
RB binding protein 4, chromatin remodeling factor
Uniprot IDQ09028
Protein Name
Histone-binding protein RBBP4
Alternate Names
CAF-1 subunit C • CAF-I 48 kDa subunit • CAF-I p48 • chromatin assembly factor 1 subunit C • chromatin assembly factor I p48 subunit • chromatin assembly factor/CAF-1 p48 subunit • histone-binding protein RBBP4 • lin-53 • MSI1 protein homolog • nucleosome-remodeling factor subunit RBAP48 • NURF55 • RBAP48 • RBBP-4 • retinoblastoma-binding protein 4 • retinoblastoma-binding protein p48
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to RbBP4 immobilized on solid support.
The epitope recognized by IHC-00242 maps to a region between residue 1 and 50 of human retinoblastoma binding protein 4 (retinoblastoma-binding protein p48) using the numbering given in entry CAA52321.1 (GeneID 5928).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00242Open
Product DatasheetPDF · IHC-00242 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00242 · Lot 1 (current lot)Open
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