Bethyl Laboratories
Rabbit anti-RbBP7 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00160
TargetRbBP7
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
Retinoblastoma-binding protein 7 (RbBP7) is a component of several complexes that regulate chromatin remodeling and assembly. RbBP7 is a subunit of the histone acetyltransferase (HAT) complex and of the core mSin3 histone deacetylase (HDAC) complex. RbBP7 is a histone binding subunit that functions to recruit chromatin assembly and remodeling factors to histones. RbBP7 also interacts with pRb and BRCA1 to modulate their activity.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 375 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetRbBP7
Antigen Species
Human
Gene ID5931
Gene Symbol
RBBP7
Gene Name
RB binding protein 7, chromatin remodeling factor
Uniprot IDQ16576
Protein Name
Histone-binding protein RBBP7
Alternate Names
G1/S transition control protein-binding protein RbAp46 • histone acetyltransferase type B subunit 2 • histone-binding protein RBBP7 • nucleosome-remodeling factor subunit RBAP46 • RbAp46 • RBBP-7 • retinoblastoma-binding protein 7 • retinoblastoma-binding protein p46 • retinoblastoma-binding protein RbAp46
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to RbBP7 immobilized on solid support.
The epitope recognized by IHC-00160 maps to a region between residue 375 and the C-terminus (residue 425) of human Retinoblastoma Binding Protein 7 using the numbering given in entry AAC50231.1 (GeneID 5931).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00160Open
Product DatasheetPDF · IHC-00160 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00160 · Lot 1 (current lot)Open
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