Bethyl Laboratories
Rabbit anti-RCOR3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00308
TargetRCOR3
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationICC-IF, IHC, IHC-IF
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Product Description
RCOR3 is a member of the coREST family that functions as a co-repressor for REST (RE1-silencing transcription factor) to regulate neuronal gene expression and neuronal stem cell fate. The coREST family includes RCOR1, also known as coREST, RCOR2, and RCOR3. REST complexes regulate gene expression by modifying chromatin to create a repressive epigenetic environment.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 445 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetRCOR3
Antigen Species
Human
Gene ID55758
Gene Symbol
RCOR3
Gene Name
REST corepressor 3
Uniprot IDQ9P2K3
Protein Name
REST corepressor 3
Alternate Names
Product Information
Applications
ICC-IF, IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to RCOR3 immobilized on solid support.
The epitope recognized by IHC-00308 maps to a region between residue 445 and 495 of human REST corepressor 3 using the numbering given in entry NP_060724.1 (GeneID 55758).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunocytochemistry-Immunofluoresence (ICC-IF)1:50 - 1:500
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00308Open
Product DatasheetPDF · IHC-00308 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00308 · Lot 1 (current lot)Open
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