Rabbit anti-RLIP76 Antibody Affinity Purified
Catalog #
RLIP76
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 605 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15311].
Alternate Names
76 kDa Ral-interacting protein; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ralA-binding protein 1; RalBP1; ral-interacting protein 1; RIP1; RLIP1; RLIP76
Applications