Bethyl Laboratories
Rabbit anti-SAFB2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00218
TargetSAFB2
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Scaffold attachment factor B2 (SAFB2) is a chromatin associated protein that interacts with DNA elements termed S/MARs (scaffold or matrix attachment regions) but is not part of the nuclear matrix. SAFB2 is structurally and functionally similar to SAFB1 and appears to be a multifunctional protein involved in chromatin organization, mRNA processing and transcriptional regulation. SAFB2 has been demonstrated to interact with and function as a corepressor with many nuclear receptors such as estrogen receptor-alpha, PPAR-gamma, and FXR-alpha.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 175 and 225
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetSAFB2
Antigen Species
Human
Gene ID9667
Gene Symbol
SAFB2
Gene Name
scaffold attachment factor B2
Uniprot IDQ14151
Protein Name
Scaffold attachment factor B2
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SAFB2 immobilized on solid support.
The epitope recognized by IHC-00218 maps to a region between residue 175 and 225 of human scaffold attachment factor B2 using the numbering given in entry NP_055464.1 (GeneID 9667).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00218Open
Product DatasheetPDF · IHC-00218 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00218 · Lot 1 (current lot)Open
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