Bethyl Laboratories

Rabbit anti-SAM68 IHC Antibody Affinity Purified

Primary
Catalog #IHC-00578
TargetSAM68
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
Detection of human SAM68 by immunohistochemistry.
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Product Description

SAM68 (Src-associated in mitosis 68 kDa protein) was identified as an SH3 and SH2 domain interacting protein. It is a Src substrate and contains a KH-type RNA binding domain. It has been shown to function as a regulator of mRNA stability, pre-mRNA processing, and RNA export.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
50 µg/ml
Target Identity
TargetSAM68
Antigen Species
Human
Gene ID10657
Gene Symbol
KHDRBS1
Gene Name
KH RNA binding domain containing, signal transduction associated 1
Uniprot IDQ07666
Protein Name
KH domain-containing, RNA-binding, signal transduction-associated protein 1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to SAM68 immobilized on solid support.

The epitope recognized by IHC-00578 maps to a region between residue 1 and 50 of human Src-associated in mitosis 68 kDa protein (KH domain containing, RNA binding, signal transduction associated 1) using the numbering given in entry NP_006550.1 (GeneID 10657).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.

Immunohistochemistry (IHC)1:100 - 1:500

Documents

Safety Data SheetPDF · IHC-00578Open
Product DatasheetPDF · IHC-00578 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00578 · Lot 1 (current lot)Open
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