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Rabbit anti-SHANK3 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
SHANK3
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1475 and 1525
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$121.00 $433.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Presumed Reactivity
Rat
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Country of Origin
USA

Additional Product Information

SH3 and multiple ankyrin repeat domains 3 (SHANK3) seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK3 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BYB0].

85358
SHANK3
SH3 and multiple ankyrin repeat domains 3
Q9BYB0
SH3 and multiple ankyrin repeat domains protein 3

Alternate Names

DEL22q13.3; proline rich synapse associated protein 2; Proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains protein 3; shank postsynaptic density protein; Shank3; SPANK-2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.