Rabbit anti-SIGLEC-15 Recombinant Monoclonal Antibody [BLR276L]
Product Details
Specifications
Additional Product Information
SIGLEC-15 is a member of the SIGLEC family that binds sialylated glycoproteins. It is expressed on a subset of myeloid cells normally but is broadly upregulated on human cancer cells and tumor-infiltrating myeloid cells. SIGLEC-15 is suggested to be involved in the regulation of bone resorption and in osteoclast development. It has also been suggested to be involved in microbial infection and the cancer microenvironment. [taken from NCBI Entrez Gene (Gene ID: 284266)].
Alternate Names
CD33 antigen-like 3;CD33 molecule-like 3;CD33L3;HsT1361;sialic acid-binding Ig-like lectin 15;SIGLEC-15
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).