Rabbit anti-SIPA1 Antibody Affinity Purified
Catalog #
SIPA1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 992 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
USA
The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Signal-induced proliferation-associated protein 1 (SIPA1) is a GTPase activating protein (GAP) for the Rap1 and Rap2 small GTPases. Spa-1 has been found to play an important role in hematopoietic cell development and the invasion and metastasis of human cancers.
Signal-induced proliferation-associated protein 1
Alternate Names
GTPase-activating protein Spa-1; p130 SPA-1; signal-induced proliferation-associated gene 1; signal-induced proliferation-associated protein 1; sipa-1; SPA1
Applications