Bethyl Laboratories
Rabbit anti-SMARCC2/BAF170 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00213
TargetSMARCC2/BAF170
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SMARCC2/BAF170 associates with SMARCA2/Brm and SMARCA4/Brg BAF complex and in cooperation with SMARCC1/BAF155, enhances chromatin remodeling activity.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1164 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetSMARCC2/BAF170
Antigen Species
Human
Gene ID6601
Gene Symbol
SMARCC2
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Uniprot IDQ8TAQ2
Protein Name
SWI/SNF complex subunit SMARCC2
Alternate Names
BAF170 • BRG1-associated factor 170 • chromatin remodeling complex BAF170 subunit • CRACC2 • mammalian chromatin remodeling complex BRG1-associated factor 170 • Rsc8 • SWI/SNF complex 170 kDa subunit • SWI/SNF complex subunit SMARCC2 • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 • SWI3-like protein
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SMARCC2/BAF170 immobilized on solid support.
The epitope recognized by IHC-00213 maps to a region between residue 1164 and the C-terminus (residue 1214) of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (BRG1-associated factor 170) using the numbering given in entry NP_003066.2 (GeneID 6601).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00213Open
Product DatasheetPDF · IHC-00213 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00213 · Lot 1 (current lot)Open
Citations / Publications
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