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Rabbit anti-SMC4 Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
SMC4
Reactivity:
Human
Applications:
ICC-IF
,WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 600 and 650
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Mouse
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to SMC4 immobilized on solid support.
The epitope recognized by A300-063A maps to a region between residues 600 and 650 of human Structural Maintenance of Chromosomes 4 using the numbering given in entry NP_005487.2 (GeneID 10051).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to SMC4 immobilized on solid support.
The epitope recognized by A300-063A-T maps to a region between residues 600 and 650 of human Structural Maintenance of Chromosomes 4 using the numbering given in entry NP_005487.2 (GeneID 10051).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Country of Origin
USA
Additional Product Information
SMC (Structural maintenance of chromosomes) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.
Structural maintenance of chromosomes protein 4
Alternate Names
CAPC; CAP-C; chromosome-associated polypeptide C; hCAP-C; SMC protein 4; SMC-4; SMC4 structural maintenance of chromosomes 4-like 1; SMC4L1; structural maintenance of chromosomes protein 4; XCAP-C homolog
Applications