/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-SMG7 Antibody
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Primary Antibodies  

Rabbit anti-SMG7 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (17)
Target:

SMG7

Reactivity:

Human

,

Mouse

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1087 and 1137

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.

9887

SMG7

SMG7, nonsense mediated mRNA decay factor

Q92540

Protein SMG7

Alternate Names

breast cancer-associated antigen SGA-56M; C1orf16; EST1 telomerase component homolog C; EST1C; EST1-like protein C; ever shorter telomeres 1C; hSMG-7; protein SMG7; SGA56M; SMG-7 homolog; smg-7 homolog, nonsense mediated mRNA decay factor

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.