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Rabbit anti-SOX10 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
SOX10
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 416 and 466
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
Pig, X. laevis, Chicken, Rat, X. tropicalis
Antigen Species
Human
Stock Concentration
40 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to SOX10 immobilized on solid support.

The epitope recognized by A305-799A-T maps to a region between residue 416 and 466 of human DOM; WS4; PCWH; WS2E; WS4C using the numbering given in entry P56693.1 (GeneID 6663).

Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX10 may act as a transcriptional activator after forming a protein complex with other proteins. SOX10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development [taken from NCBI Entrez Gene (Gene ID: 6663)].

6663

SOX10

SRY-box 10

P56693

Transcription factor SOX-10

Alternate Names

DOM, dominant megacolon, mouse, human homolog of, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS2E, WS4, WS4C

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE