Bethyl Laboratories

Rabbit anti-SRcyp IHC Antibody Affinity Purified

Primary
Catalog #IHC-00547
TargetSRcyp
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
Detection of human SRcyp by immunohistochemistry.
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Product Description

SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 450 and 500
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetSRcyp
Antigen Species
Human
Gene ID9360
Gene Symbol
PPIG
Gene Name
peptidylprolyl isomerase G
Uniprot IDQ13427
Protein Name
Peptidyl-prolyl cis-trans isomerase G
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to SRcyp immobilized on solid support.

The epitope recognized by IHC-00547 maps to a region between residue 450 and 500 of human SR-cyclophilin (Peptidyl-prolyl isomerase G) using the numbering given in entry NP_004783.2 (GeneID 9360).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.

Immunohistochemistry (IHC)1:100 - 1:500

Documents

Safety Data SheetPDF · IHC-00547Open
Product DatasheetPDF · IHC-00547 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00547 · Lot 1 (current lot)Open
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