Rabbit anti-SRPK1 IHC Antibody
Catalog #
SRPK1
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 275 and 325
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Guinea_pig,
Horse,
Dog,
Pig,
Rabbit,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
Serine/arginine rich protein-specific kinase 1 (SRPK1) plays a central role in the regulatory network for splicing by controlling the intranuclear distribution of splicing factors in interphase cells and the re-organization of nuclear speckles during mitosis. During metaphase, SRPK1 hyperphosphorylates RS domain-containing proteins such as SFRS1 and SFRS2 on serine residues. SRPK1 also appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96SB4].
Alternate Names
Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SFRSK1; SR-protein-specific kinase 1; SRSF protein kinase 1
Applications
