Bethyl Laboratories
Rabbit anti-SSB1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00403
TargetSSB1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
Single-stranded DNA -binding protein (SSB1) is phosphorylated by ATM in response to DNA damage. SSB1 is required for checkpoint activation and is critical for genomic stability.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 161 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetSSB1
Antigen Species
Human
Gene ID79035
Gene Symbol
NABP2
Gene Name
nucleic acid binding protein 2
Uniprot IDQ9BQ15
Protein Name
SOSS complex subunit B1
Alternate Names
hSSB1 • LP3587 • Nucleic acid-binding protein 2 • OBFC2B • oligonucleotide/oligosaccharide-binding fold containing 2B • oligonucleotide/oligosaccharide-binding fold-containing protein 2B • sensor of single-strand DNA complex subunit B1 • sensor of ssDNA subunit B1 • single strand DNA-binding protein 1 • single-stranded DNA-binding protein 1 • SOSS complex subunit B1 • SOSS-B1 • SSB1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SSB1 immobilized on solid support.
The epitope recognized by IHC-00403 maps to a region between residue 161 and 211 of human single-stranded DNA-binding protein 1 using the numbering given in entry NP_076973.1 (GeneID 79035).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate or tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00403Open
Product DatasheetPDF · IHC-00403 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00403 · Lot 1 (current lot)Open
Citations / Publications
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Resources
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