Bethyl Laboratories
Rabbit anti-SUV39H1 Antibody Affinity Purified
Primary
Catalog #A302-127A
TargetSUV39H1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP, WB
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Product Description
SUV39H1 (suppressor of variegation 3-9 homolog 1) is a histone methyltransferase that specifically trimethylates histone H3 at lys 9. Trimethylation stimulates the binding of heterochromatin proteins (HPs) which leads to epigenetic transcriptional repression in heterochromatin regions.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 50 and 100
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
200 µg/ml
Target Identity
TargetSUV39H1
Antigen Species
Human
Gene ID6839
Gene Symbol
SUV39H1
Gene Name
suppressor of variegation 3-9 homolog 1
Uniprot IDO43463
Protein Name
Histone-lysine N-methyltransferase SUV39H1
Alternate Names
H3-K9-HMTase 1 • histone H3-K9 methyltransferase 1 • histone-lysine N-methyltransferase SUV39H1 • histone-lysine N-methyltransferase, H3 lysine-9 specific 1 • KMT1A • lysine N-methyltransferase 1A • MG44 • position-effect variegation 3-9 homolog • Su(var)3-9 homolog 1 • Suppressor of variegation 3-9 homolog 1 • SUV39H
Product Information
Applications
IP, WB
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SUV39H1 immobilized on solid support.
The epitope recognized by A302-127A maps to a region between residue 25 and 75 of human suppressor of variegation 3-9 homolog 1 using the numbering given in entry NP_003164.1 (GeneID 6839).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Western Blot (WB)1:2000 - 1:10,000
Documents
Product DatasheetPDF · A302-127A · Lot 1 (current lot)Open
Product DatasheetPDF · A302-127A · Lot 1 (current lot)Open
Safety Data SheetPDF · A302-127AOpen
Citations / Publications
Services
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