Rabbit anti-SYK Antibody Affinity Purified
Catalog #
SYK
Human
IHC
,IP
Rabbit
Polyclonal
Whole IgG
Between 250 and 300
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
SYK (spleen tyrosine kinase) is a ubiquitously expressed tyrosine kinase that functions in mediating B and T-cell receptor signaling and is also important to various aspects of leukocyte function that involve cytoskeleton remodeling. In mediating hematopoietic cell signaling, SYK is a substrate of src family kinase activity and is a key-regulator of Akt kinase activity. SYK has also been found to be highly expressed in the mammary gland and has been shown to inhibit tumor growth and metastasis. Invasive breast tumor cell lines have been shown to exhibit reduced or absent levels of SYK, further implicating a role in tumorigenesis and metastasis.
Alternate Names
p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK
Applications