Bethyl Laboratories
Rabbit anti-Tankyrase 1 Antibody Affinity Purified
Primary
Catalog #A302-398A
TargetTankyrase 1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP
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Product Description
Tankyrase-1 is a poly(ADP-ribose) polymerase that localizes to telomeres via its interaction with TRF1. Tankyrase modifies and associates with multiple proteins and appears to be involved in the maintenance of telomere length, sister telomere association, mitotic spindle organization, and trafficking of glut4-containing vesicles.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
TargetTankyrase 1
Antigen Species
Human
Gene ID8658
Gene Symbol
TNKS
Gene Name
tankyrase
Uniprot IDO95271
Protein Name
Tankyrase-1
Alternate Names
ADP-ribosyltransferase diphtheria toxin-like 5 • ARTD5 • PARP5A • PARP-5a • PARPL • pART5 • poly [ADP-ribose] polymerase 5A • TANK1 • tankyrase I • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase • tankyrase-1 • TIN1 • TINF1 • TNKS1 • TNKS-1 • TRF1-interacting ankyrin-related ADP-ribose polymerase • TRF1-interacting ankyrin-related ADP-ribose polymerase 1
Product Information
Applications
IP
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Tankyrase 1 immobilized on solid support.
The epitope recognized by A302-398A maps to a region between residue 1 and 50 of human TRF1-interacting ankyrin-related ADP-ribose polymerase using the numbering given in entry NP_003738.2 (GeneID 8658).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Documents
Product DatasheetPDF · A302-398A · Lot 1 (current lot)Open
Product DatasheetPDF · A302-398A · Lot 1 (current lot)Open
Safety Data SheetPDF · A302-398AOpen
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