Rabbit anti-TDG Antibody Affinity Purified
Catalog #
TDG
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 360 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine [taken from NCBI Entrez Gene (Gene ID: 6996)].
Alternate Names
G/T mismatch-specific thymine DNA glycosylase; hTDG; Thymine-DNA glycosylase
Applications