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Rabbit anti-TFAM Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
TFAM
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 146 and 196
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to TFAM immobilized on solid support.

The epitope recognized by A303-225A-T maps to a region between residue 146 and 196 of human Transcription Factor A, Mitochondrial using the numbering given in entry NP_003192.1 (GeneID 7019).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

Transcription factor A, mitochondrial (TFAM) binds to the mitochondrial light strand promoter and functions in mitochondrial transcriptional regulation. TFAM is required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase and promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. TFMA is required for maintenance of normal levels of mitochondrial DNA and may play a role in organizing and compacting mitochondrial DNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q00059].

7019

TFAM

transcription factor A, mitochondrial

Q00059

Transcription factor A, mitochondrial

Alternate Names

mitochondrial transcription factor 1, mitochondrial transcription factor A, MTDPS15, MTTF1, MTTFA, TCF6, TCF-6, TCF6L1, TCF6L2, TCF6L3, transcription factor 6, transcription factor 6-like 1, Transcription factor 6-like 2, transcription factor 6-like 2 (mitochondrial transcription factor), transcription factor 6-like 3, transcription factor A, mitochondrial

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-12% SDS-PAGE.