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Primary Antibodies

Rabbit anti-TfR Antibody Affinity Purified

Name: Rabbit anti-TfR Antibody
Brand: Bethyl Laboratories®
SKU: A304-381A
Price: 121 USD

Bethyl Laboratories®

Catalog #

Citations (2)

Target:

TfR

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 125 and 175

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications

Verified Reactivity

Human

Presumed Reactivity

Horse,

Dog

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

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Additional Product Information

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor (TR) into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P02786].

Gene ID:

7037

Gene Symbol:

TFRC

Gene Name:

transferrin receptor

Uniprot ID:

P02786

Protein Name:

Transferrin receptor protein 1

Alternate Names

CD antigen CD71; CD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Rabbit anti-TfR Antibody Affinity Purified

Catalog #

TfR

Human

WB

Rabbit

Polyclonal

Whole IgG

Between 125 and 175

IgG

Unconjugated

Antigen Affinity Purified

Human

Horse,

Dog

Human

2 - 8 °C

1 year from date of receipt

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

7037

TFRC

transferrin receptor

P02786

Transferrin receptor protein 1

CD antigen CD71; CD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).