Bethyl Laboratories
Rabbit anti-THOC1 Antibody Affinity Purified
Primary
Catalog #A302-838A
TargetTHOC1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IP
Image 1 of 2
local_shipping
Order within 12 hours and 37 minutes for shipment by today
Product Description
THO complex subunit 1 (THOC1) is a component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and UAP56, THO forms a complex with the transcription/export (TREX) complex. The TREX complex specifically associates with spliced mRNA and functions in mRNA export.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 550 and 600
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
TargetTHOC1
Antigen Species
Human
Gene ID9984
Gene Symbol
THOC1
Gene Name
THO complex 1
Uniprot IDQ96FV9
Protein Name
THO complex subunit 1
Alternate Names
HPR1 • hTREX84 • nuclear matrix protein p84 • P84 • P84N5 • THO complex subunit 1 • tho1
Product Information
Applications
IHC, IP
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to THOC1 immobilized on solid support.
The epitope recognized by A302-838A maps to a region between residue 550 and 600 of human THO Complex 1 using the numbering given in entry NP_005122.2 (GeneID 9984).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunohistochemistry (IHC)1:500 - 1:2000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Immunoprecipitation (IP)6 µg/mg lysate
Documents
Product DatasheetPDF · A302-838A · Lot 1 (current lot)Open
Product DatasheetPDF · A302-838A · Lot 1 (current lot)Open
Safety Data SheetPDF · A302-838AOpen
Services
Antibody Conjugation
Antibody and conjugate formats developed together, built to your specification.
Request CustomizationCustom Monoclonal Antibody Discovery Services
Full custom monoclonal development, from immunization through validation.
Explore Monoclonal DevelopmentVHH Discovery
Single-domain antibodies for structurally difficult targets a conventional monoclonal can't reach.
Explore VHH DiscoveryResources
1