Rabbit anti-TRAP100/MED24 Antibody Affinity Purified
Catalog #
TRAP100/MED24
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 939 and 989
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Chicken,
Rat
Human
2 - 8 °C
1 year from date of receipt
TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development.
Mediator of RNA polymerase II transcription subunit 24
Alternate Names
activator-recruited cofactor 100 kDa component; ARC100; cofactor required for Sp1 transcriptional activation subunit 4; cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa; CRSP complex subunit 4; CRSP100; CRSP4; DRIP100; hTRAP100; MED5; Mediator complex subunit 24; mediator of RNA polymerase II transcription subunit 24; mediator of RNA polymerase II transcription, subunit 24 homolog; THRAP4; thyroid hormone receptor-associated protein 4; thyroid hormone receptor-associated protein complex 100 kDa component; TRAP100; vitamin D3 receptor-interacting protein complex 100 kDa component; vitamin D3 receptor-interacting protein complex component DRIP100
Applications