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Rabbit anti-TRPC3 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

TRPC3

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 275 and 325

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Transient receptor protein 3 (TRPC3) is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC3 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. It may also be activated by internal calcium store depletion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13507].

7222

TRPC3

transient receptor potential cation channel subfamily C member 3

Q13507

Short transient receptor potential channel 3

Alternate Names

hTrp3; hTrp-3; SCA41; short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor protein 3; TRP3; TRP-3; TrpC3

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.