Rabbit anti-TS Antibody
Catalog #
TS
Human
,Mouse
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 263 and 313
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Dog,
Pig,
Rabbit,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].
Alternate Names
HST422; thymidylate synthase; TMS; TS; TSase
Applications