Bethyl Laboratories

Rabbit anti-WDR79 IHC Antibody Affinity Purified

Primary
Catalog #IHC-00534
TargetWDR79
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
Detection of human WDR79 immunohistochemistry.
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Product Description

WD-repeat domain 79 (WDR79) contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetWDR79
Antigen Species
Human
Gene ID55135
Gene Symbol
WRAP53
Gene Name
WD repeat containing antisense to TP53
Uniprot IDQ9BUR4
Protein Name
Telomerase Cajal body protein 1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to WDR79 immobilized on solid support.

The epitope recognized by IHC-00534 maps to a region between residue 1 and 50 of human WD repeat domain 79 using the numbering given in entry NP_060551.1 (GeneID 55135).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.

Immunohistochemistry (IHC)1:100 - 1:500

Documents

Safety Data SheetPDF · IHC-00534Open
Product DatasheetPDF · IHC-00534 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00534 · Lot 1 (current lot)Open
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