Rabbit anti-WRN Recombinant Monoclonal Antibody [BLR333M]
Product Details
Specifications
Request Formulation Change Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free
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Immunogen was a peptide representing a region between residue 1382 and the C-terminus (residue 1432) of human ATP-dependent helicase WRN using the numbering given in entry NP_000544.2 (Gene ID 7486).
Additional Product Information
The protein product of the Werner’s syndrome (WRN) gene is the Werner syndrome ATP-dependent helicase. WRN is part of the ReqQ family of helicases that unwind DNA in preparation for replication, transcription, and repair. WRN appears to play a versatile role in cellular processes including DNA replication, transcription and the maintenance of genomic integrity.
Alternate Names
DNA helicase, RecQ-like type 3; exonuclease WRN; recQ protein-like 2; RECQ3; RECQL2; RECQL3; Werner syndrome ATP-dependent helicase; Werner syndrome, RecQ helicase-like
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.