Bethyl Laboratories
Rabbit anti-XRN2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00223
TargetXRN2
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IHC-IF
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Product Description
XRN2 is a 5’-to-3’ exoribonuclease involved in 3’-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3’-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3’-end processing machinery by p54nrb/PSF.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 900 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetXRN2
Antigen Species
Human
Gene ID22803
Gene Symbol
XRN2
Gene Name
5'-3' exoribonuclease 2
Uniprot IDQ9H0D6
Protein Name
5'-3' exoribonuclease 2
Alternate Names
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to XRN2 immobilized on solid support.
The epitope recognized by IHC-00223 maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00223Open
Product DatasheetPDF · IHC-00223 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00223 · Lot 1 (current lot)Open
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