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Rabbit anti-XRN2 IHC Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
XRN2
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 900 and 950
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
White-tufted-ear marmoset, Crab-eating macaque, Monkey, African elephant, Little brown bat, Chimpanzee, Northern white-cheeked gibbon, Orangutan
Antigen Species
Human
Stock Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to XRN2 immobilized on solid support.

The epitope recognized by IHC-00223-T maps to a region between residue 900 and 950 of human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).

Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

XRN2 is a 5’-to-3’ exoribonuclease involved in 3’-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3’-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3’-end processing machinery by p54nrb/PSF.

22803

XRN2

5'-3' exoribonuclease 2

Q9H0D6

5'-3' exoribonuclease 2

Alternate Names

5'-3' exoribonuclease 2, Dhm1-like protein, DHP protein

Applications

Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.

Citations (1)