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Rabbit anti-YB1 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
YB1
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 224 and 274
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
X. laevis, Rabbit, Bovine, Chicken, Rat
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to YB1 immobilized on solid support.

The epitope recognized by A303-230A-T maps to a region between residue 224 and 274 of human Y Box Binding Protein 1 using the numbering given in entry NP_004550. (GeneID 4904).

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Gene & Protein Information

Y-box-binding protein 1 (YB1) Regulates the transcription of numerous genes. It has been shown to promote separation of DNA strands that contain mismatches or are modified by cisplatin, and shown to have endonucleolytic activity that can introduce nicks or breaks into double-stranded DNA (in vitro). YB1 may play a role in DNA repair. It is a component of the CRD-mediated complex that promotes MYC mRNA stability [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P67809].

4904

YBX1

Y-box binding protein 1

P67809

Nuclease-sensitive element-binding protein 1

Alternate Names

BP-8, CBF-A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA-binding protein B, EFI-A, enhancer factor I subunit A, major histocompatibility complex, class II, Y box-binding protein I, MDR-NF1, NSEP1, NSEP-1, nuclease-sensitive element-binding protein 1, YB1, YB-1, Y-box transcription factor, Y-box-binding protein 1

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.

Citations (2)