Bethyl Laboratories
Rabbit anti-ZCCHC8 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00353
TargetZCCHC8
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
50 µg/ml
Target Identity
TargetZCCHC8
Antigen Species
Human
Gene ID55596
Gene Symbol
ZCCHC8
Gene Name
zinc finger CCHC-type containing 8
Uniprot IDQ6NZY4
Protein Name
Zinc finger CCHC domain-containing protein 8
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ZCCHC8 immobilized on solid support.
The epitope recognized by IHC-00353 maps to a region between residue 1 and 50 of human zinc finger, CCHC domain containing 8 using the numbering given in entry NP_060082.2 (GeneID 55596).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00353Open
Product DatasheetPDF · IHC-00353 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00353 · Lot 1 (current lot)Open
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