Bethyl Laboratories
Rabbit anti-ZHX3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00299
TargetZHX3
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
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Product Description
ZHX3 (zinc-fingers and homeoboxes 3) was identified as a factor that heterodimerizes with the transcriptional repressor, ZHX1. ZHX3 has also been found to partner with ZHX2 and itself, as a dimer, to play a role in transcriptional repression. Recently, studies in a rat model for proteinuria have revealed an important role for ZHX3 in glomerular disease development and the regulation of gene expression in glomerular podocytes.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 150 and 200
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetZHX3
Antigen Species
Human
Gene ID23051
Gene Symbol
ZHX3
Gene Name
zinc fingers and homeoboxes 3
Uniprot IDQ9H4I2
Protein Name
Zinc fingers and homeoboxes protein 3
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ZHX3 immobilized on solid support.
The epitope recognized by IHC-00299 maps to a region between residue 150 and 200 of human zinc fingers and homeoboxes 3 using the numbering given in entry NP_055850.1 (GeneID 23051).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00299Open
Product DatasheetPDF · IHC-00299 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00299 · Lot 1 (current lot)Open
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