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Rabbit anti-ZNF198 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
ZNF198
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1327 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

10 µl (200 µg/ml)

$121.00 $433.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Presumed Reactivity
Mouse
Antigen Species
Human
Concentration
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Country of Origin
USA

Additional Product Information

ZNF198 contains nine MYM-type zinc fingers. The N-terminal half of the ZNF198 gene has been identified as a gene fused to the cytoplasmic domain of the fibroblast growth factor receptor (FGFR1) gene as a result of a t(8;13) (p11;q11-12) chromosomal rearrangement. The t(8;13) chromosomal translocation is associated with myeloproliferative diseases such as stem cell leukemia lymphoma syndrome (SCLL). Studies of the normal function of ZNF198 have revealed that it associates with HHR6 and RAD18 and may be involved in the repair of DNA. ZNF198 has also been found to associate with the BHC110 subunit of a histone-deacetylase containing corepressor complex and may have an additional function in transcriptional repression.

7750
ZMYM2
zinc finger MYM-type containing 2
Q9UBW7
Zinc finger MYM-type protein 2

Alternate Names

FIM; fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; SCLL; zinc finger MYM-type protein 2; zinc finger protein 198; zinc finger, MYM-type 2; ZNF198

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.