Bethyl Laboratories
Rabbit anti-ZWINT-1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00095
TargetZWINT-1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationICC-IF, IHC
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Product Description
Yeast 2-hybrid and localization studies show that human ZW10 interacting protein 1 (ZWINT-1) interacts with HZw10 in active centromeres and may play a role in directing HZw10 to the kinetochore during prometaphase. HZw10 is a component of the mitotic checkpoint that associates with the kinetochore to ensure chromosome fidelity during cell division.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 227 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetZWINT-1
Antigen Species
Human
Gene ID11130
Gene Symbol
ZWINT
Gene Name
ZW10 interacting kinetochore protein
Uniprot IDO95229
Protein Name
ZW10 interactor
Product Information
Applications
ICC-IF, IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to ZWINT-1 immobilized on solid support.
The epitope recognized by IHC-00095 maps to a region between residue 225 and the C-terminus (residue 277) of human ZW10 Interactor-1 using the numbering given in entry NP_008988.2 (GeneID 11130).
Applications
Formalin-Fixed Paraffin-Embedded Tissue 1:100 - 1:500:
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Formaldehyde-Fixed Cells 1:100 - 1:500.
Immunocytochemistry-Immunofluoresence (ICC-IF)1:100 - 1:500
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00095Open
Product DatasheetPDF · IHC-00095 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00095 · Lot 1 (current lot)Open
Citations / Publications
Services
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