Bethyl Laboratories
Rabbit anti-PBEF IHC Antibody Affinity Purified
Primary
Catalog #IHC-00011
TargetPBEF
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
PBEF is also known as visfatin and was first identified as a factor that enhanced the differentiation of B-cells. It is a secreted factor that is highly expressed in adipocytes. Intracellularly, PBEF acts as a cytosolic enzyme involved in nicotinamide adenine dinucleotide (NAD) synthesis. PBEF levels positively correlate with obesity and type 2 diabetes mellitus and can bind the insulin receptor to lower blood sugar.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 400 and 450
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetPBEF
Antigen Species
Human
Gene ID10135
Gene Symbol
NAMPT
Gene Name
nicotinamide phosphoribosyltransferase
Uniprot IDP43490
Protein Name
Nicotinamide phosphoribosyltransferase
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to PBEF immobilized on solid support.
The epitope recognized by IHC-00011 maps to a region between residue 400 and 450 of human pre-B-cell colony enhancing factor using the numbering given in SwissProt entry P43490 (GeneID 10135).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00011Open
Product DatasheetPDF · IHC-00011 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00011 · Lot 1 (current lot)Open
Citations / Publications
Services
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