Bethyl Laboratories
Rabbit anti-Phospho Aurora A (T288) IHC Antibody Affinity Purified
Primary
Catalog #IHC-00067
TargetAurora A Phospho (T288)
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationICC-IF
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Product Description
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Surrounding threonine 288
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetAurora A Phospho (T288)
Antigen Species
Human
Gene ID6790
Gene Symbol
AURKA
Gene Name
aurora kinase A
Uniprot IDO14965
Protein Name
Aurora kinase A
Alternate Names
AIK • ARK1 • ARK-1 • AURA • aurora 2 • aurora kinase A • aurora/IPL1-like kinase • aurora/IPL1-related kinase 1 • Aurora-related kinase 1 • breast tumor-amplified kinase • BTAK • hARK1 • PPP1R47 • protein phosphatase 1, regulatory subunit 47 • serine/threonine protein kinase 15 • Serine/threonine-protein kinase 15 • serine/threonine-protein kinase 6 • serine/threonine-protein kinase aurora-A • STK15 • STK6 • STK7
Product Information
Applications
ICC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Phospho Aurora A (T288) immobilized on solid support.
The epitope recognized by IHC-00067 maps to a region surrounding residue 288 when Threonine 288 is phosphorylated of human Aurora A Kinase using the numbering given entry NP_003591.2 (GeneID 6790).
Applications
Formaldehyde-Fixed Cells 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunocytochemistry-Immunofluoresence (ICC-IF)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00067Open
Product DatasheetPDF · IHC-00067 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00067 · Lot 1 (current lot)Open
Citations / Publications
Services
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