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Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified [KP-1]

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
CD68
Reactivity:
Human
Host:
Mouse
Clonality:
Recombinant Monoclonal
Clone:
KP-1
Format:
Whole IgG
Immunogen:
Lysosomal fraction of human lung macrophages
IsoType:
IgG1
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
50 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
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Prod Procedures
VH and VL were cloned from the KP-1 hybridoma. Recombinant antibody was purified from cell culture supernatant.

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Gene & Protein Information

CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].

968

CD68

CD68 molecule

P34810

Macrosialin

Alternate Names

CD antigen CD68, CD68 antigen, GP110, LAMP4, macrophage antigen CD68, macrosialin, SCARD1, scavenger receptor class D, member 1