/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-4-1BBL/CD137L/TNFSF9 Recombinant Monoclonal Antibody [BLR148J]
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Rabbit anti-4-1BBL/CD137L/TNFSF9 Recombinant Monoclonal Antibody [BLR148J]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

4-1BBL/CD137L/TNFSF9

Reactivity:

Human

Applications:

Flow Cyt

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR148J

Format:

Whole IgG

Immunogen:

Residues 71-254 (ECD)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

$127.00 $306.00
Qty:
Bulk Request

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide


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Production Procedures

Recombinant antibody was purified from cell culture supernatant.

Immunogen was a recombinant protein representing the extracellular domain of human Tumor necrosis factor ligand superfamily member 9 (TNFSF9, aka 4-1BBL, CD137L; residues 71-254, NP_003802.1).

Country of Origin

USA

Additional Product Information

4-1BBL (aka CD137L or TNFSF9) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. 4-1BBL and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells; they are also involved in promoting T lymphocyte proliferation. 4-1BBL has been shown to be required for the optimal CD8 responses in CD8 T cells. 4-1BBL is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [taken from NCBI Entrez Gene (Gene ID: 8744)].

8744

TNFSF9

TNF superfamily member 9

P41273

Tumor necrosis factor ligand superfamily member 9

Alternate Names

4-1BB ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNLG5A; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).