Rabbit anti-53BP1 Antibody Affinity Purified
Catalog #
53BP1
Human
,Mouse
WB
Rabbit
Polyclonal
Whole IgG
Between 1922 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
USA
53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage.
Alternate Names
53BP1; p202; p53-binding protein 1; p53BP1; TDRD30; TP53-binding protein 1; tumor protein 53-binding protein, 1; tumor suppressor p53-binding protein 1
Applications